Transcription Factor Binding
FactorPath™
ChIP-Seq | ChIP-on-Chip | Query qPCR

Genome-wide discovery, identification, validation, and quantitation of transcription factor binding sites

Assays include: ChIP experimental design and consultation, antibody qualification, performance of ChIP assay, post-ChIP QC by PCR, amplification or library generation, post-amplification QC by PCR, and comprehensive data analysis

Price: Inquire

Gene transcription—the primary level at which compounds and other changes exert their effects within cells—is controlled by the interactions between transcription factor proteins and their binding sites. Detection of the specific DNA binding sites of transcription factors in the genome is therefore fundamental to understanding the complex and varied regulatory pathways that direct gene expression in the cell and govern all biological processes, including disease development.

FactorPath™ identifies and quantifies the precise genomic DNA binding sites of specific transcription factors and co-regulatory factors with a high level of accuracy, sensitivity, and reproducibility. Through direct measurement of the interactions between DNA and transcription factors that occur inside the nucleus of living cells and tissues, FactorPath generates highly specific and quantitative information valuable for identifyng and studying unique genetic regulatory events, genetic pathways, and novel biomarkers.