Histone Modification
HistonePath™
ChIP-Seq | ChIP-on-Chip | Query qPCR

Genome-wide discovery, identification, validation, and quantitation of histone modifications

Assays include: ChIP experimental design and consultation, antibody qualification, performance of ChIP assay, post-ChIP QC by PCR, amplification or library generation, post-amplification QC by PCR, and comprehensive data analysis

Price: Inquire

Modification of DNA-associated histone proteins involving acetylation, methylation, phosphorylation, and ubiquitination affect the structure of chromatin and its availability for transcription initiation, replication, and repair.

HistonePath™ enables accurate, reproducible identification of histone modifications across the genome with high sensitivity and specificity, enabling identification of tissue- or disease-specific histone modification patterns, identification of novel histone modification biomarkers for disease onset and progression, and correlation of histone protein status directly with expression profiles.